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With a PhD in molecular pathology from the University of California at Davis, Dr. Writing thought-provoking books, blog posts and TedX Talks isnвЂ™t KnoepflerвЂ™s only passion. To help patients, he decided to speak out against these clinics on his blog, вЂњ The Niche,вЂќ and lab website at first, but since has expanded to all sorts of outlets and publications, including his own TedX talk in 2017 on CRISPR. His start in science communication began during his post-doc years when working in a lab researching cancer and stem cells, he came across many clinics selling stem cells that are not FDA approved. For example, if вЂњbrought back to life,вЂќ scientists would need to consider the mammothвЂ™s survival in our current climate-changed world.Д¬ommunicating about science has always been one of KnoepflerвЂ™s passions. This question can be asked to people trying to bring back creatures such as the woollyВ mammoth. вЂњWhy are you doing this in the first place?вЂќ he said researchers should ask themselves. He urges these researchers to consider the realistic applications of this goal. Knoepfler also points to scientists involved in so-called вЂњde-extinction,вЂ™ or the field of study that works to bring back extinct species through the gene-editing of DNA samples to construct the first of an extinct species. вЂњPeople may be trying to actually do this kind of thing on a more moderate scale in labs around the world and there are not necessarily a lot of obstacles to trying to make entirely new organisms,вЂќ he said. Knoepfler highlighted the capacity of CRISPR as being key for changing components of the combined genomes.ДЄlthough he knows that some aspects of the book are fantasy, Knoepfler said that scientists may already be working on similar gene-editing projects for various purposes. Knoepfler, on the other hand, focused on the science that would be necessary to realistically create an organism with these defining characteristics.ДЄfter comparing many birds and reptiles, the father-daughter team settled on the Komodo dragon and the Draco lizard as possible candidates whose DNA could help genetically build a dragon. His daughter did extensive research on the history of the fantastical beast, outlining key characteristics that identify a dragon in folklore, like their gigantic wings and fire-breathing capabilities.

вЂњThat really struck me as cool,вЂќ Knoepfler said.

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KnoepflerвЂ™s daughter hypothesized how to make a dragon and the two of them continued the project by writing the book as a team. вЂњWhat she proposed to her teacher was not sort of the typical science experiment,вЂќ Knoepfler said.

The inspiration for this book came from his daughterвЂ™s science fair project. Knoepfler examines the possibility of creating a dragon in his most recent book called вЂњHow to Build a Dragon or Die Trying? A Satirical Look at Cutting-Edge Science,вЂќ which has been named one of the top science fiction books of 2019 by NPR and Nature. But according to cell biologist and science communicator Paul Knoepfler, creating a dragon-like creature using CRISPR-a tool to alter DNA to change the function of a gene-might not be such a far-fetched idea. Is it possible to create a dragon using modern technology? Most people would probably think itвЂ™s impossible.